Research progress in the development of organic small molecule fluorescent probes for detecting H2O2. Issue 31 (7th June 2019)

• Record Type: Journal Article
• Authors: Liu, Yuanyuan; Jiao, Chunpeng; Lu, Wenjuan; Zhang, Pingping; Wang, Yanfeng
• Is Part Of: RSC advances. Volume 9:Issue 31(2019)
• Page Start: 18027
• Page End: 18041
• Publication Date: 2019-06-07
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra02467k
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : This review mainly summarized and introduced five types of H2 O2 -specific fluorescent probes in probes treasury based on their response group and discussed the molecular mechanism, current situation and prospects of H2 O2 fluorescent probes. Abstract : Hydrogen peroxide (H2 O2 ), as an important signaling molecule during biological metabolism, is a key member of the reactive oxygen species (ROS) family. The excess of H2 O2 will lead to oxidative stress, which is a crucial factor in the production of various ROS-related diseases. In order to study the diverse biological roles of H2 O2 in cells and animal tissues, many methods have been developed to detect H2 O2 . Recently, fluorescence imaging has attracted more and more attention because of its high sensitivity, simple operation, experimental feasibility, and real-time online monitoring. Based on the response group, this study will review the research progress on hydrogen peroxide and summarizes the mechanisms, actualities and prospects of fluorescent probes for H2 O2 .