Photo-accelerated "click" reaction between diarylsydnones and ring-strained alkynes for bioorthogonal ligation. Issue 50 (5th June 2019)
- Record Type:
- Journal Article
- Title:
- Photo-accelerated "click" reaction between diarylsydnones and ring-strained alkynes for bioorthogonal ligation. Issue 50 (5th June 2019)
- Main Title:
- Photo-accelerated "click" reaction between diarylsydnones and ring-strained alkynes for bioorthogonal ligation
- Authors:
- Zhang, Xiaocui
Wu, Xueting
Jiang, Shichao
Gao, Jingshuo
Yao, Zhuojun
Deng, Jiajie
Zhang, Linmeng
Yu, Zhipeng - Abstract:
- Abstract : A novel photo-click ligation reaction between diarylsydnones and ring-strained alkynes, exhibiting decent bioorthogonality, was established under 405 nm light irradiation. Abstract : We constructed a library of diarylsydnone (DASyd) candidates in search of a photoclickable reaction toward alkynes, enabling an ultra-accelerated reactivity, while suppressing the background cycloaddition in the dark. The in vitro and in vivo protein labelling experiments revealed that the photo-accelerated DASyd–alkyne cycloaddition exhibits robust selectivity.
- Is Part Of:
- Chemical communications. Volume 55:Issue 50(2019)
- Journal:
- Chemical communications
- Issue:
- Volume 55:Issue 50(2019)
- Issue Display:
- Volume 55, Issue 50 (2019)
- Year:
- 2019
- Volume:
- 55
- Issue:
- 50
- Issue Sort Value:
- 2019-0055-0050-0000
- Page Start:
- 7187
- Page End:
- 7190
- Publication Date:
- 2019-06-05
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c9cc02882j ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 10865.xml