Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective. (3rd April 2019)

• Record Type: Journal Article
• Authors: Ahmad, Sumayya; Lopez, Michelle; Attala, Marwan; Galor, Anat; Stanciu, Natalie A.; Miller, Darlene; Suh, Leejee; Albini, Thomas; Perez, Victor L.; Karp, Carol L.; Davis, Janet L.; Alfonso, Eduardo; Forster, Richard K.; Amescua, Guillermo
• Is Part Of: Ocular immunology and inflammation. Volume 27:Number 3(2019)
• Page Start: 499
• Page End: 506
• Publication Date: 2019-04-03
• Subjects: Infectious scleritis -- Pseudomonas -- review -- steroids; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2017.1372484
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To identify interventional factors associated with improved visual results and faster time to resolution for patients with Pseudomonas scleritis. Methods : Retrospective study analyzing inciting factors, therapeutic modalities, and outcomes of patients with Pseudomonas scleritis. Results : A total of 24 patients were analyzed; 22 were treated as outpatients. All had resolution of infection and 58% ( n = 14) maintained ≥20/200 vision. Medical therapy included topical and oral antibiotics; seven received additional subconjunctival injections; two were admitted for IV antibiotics. Patients presenting with ≥20/200 vision were more likely to maintain this level of vision ( n = 8, 80%) compared to those presenting with severe vision loss ( n = 5, 36%) ( p = 0.04). A similar proportion of patients who received ( n = 8, 61%) and did not receive ( n = 5, 39%) oral steroids achieved 20/200 vision or better once infection resolved, p = 1.0. Conclusions: Pseudomonas scleritis can be successfully managed in the outpatient setting. Oral steroids do not appear harmful in the treatment of this disease.