A fast-responsive two-photon fluorescent probe for monitoring endogenous HClO with a large turn-on signal and its application in zebrafish imaging. Issue 29 (28th May 2019)

• Record Type: Journal Article
• Authors: Wang, Jian-Yong; Qu, Jianbo; Zhang, Haitao; Wei, Kang; Ni, Shan-Xiu
• Is Part Of: RSC advances. Volume 9:Issue 29(2019)
• Page Start: 16467
• Page End: 16471
• Publication Date: 2019-05-28
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra02160d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Fast-responsive two-photon fluorescent probeNS-ClO for imaging endogenous HClO in vivo with a large turn-on signal (about 860 times) and Stokes shift (about 90 nm), fast response (about 1 min) and good selectivity. Abstract : A novel fast-responsive two-photon fluorescent probeNS-ClO was constructed for imaging endogenous HClO in living cells, tissues and fresh zebrafish with a large turn-on signal (about 860 times) and Stokes shift (about 90 nm). The probeNS-ClO for the recognition of HClO in vivo exhibited fast response (about 1 min) and good selectivity; thus, it might be a useful tool to understand the role of HClO in various physiological processes.