A flexible and multifunctional metal–organic framework as a matrix for analysis of small molecules using laser desorption/ionization mass spectrometry. Issue 48 (28th May 2019)

• Record Type: Journal Article
• Authors: Ma, Wen; Xu, Shuting; Ai, Wanpeng; Lin, Cheng; Bai, Yu; Liu, Huwei
• Is Part Of: Chemical communications. Volume 55:Issue 48(2019)
• Page Start: 6898
• Page End: 6901
• Publication Date: 2019-05-28
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc02611h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Fast screening of multi-functional MOFs as SALDI-MS matrices for the detection of small molecules and simultaneous enrichment and detection of analytes. Abstract : A variety of functional metal–organic frameworks (MOFs) were prepared via a universal method and served as matrices in small molecule analysis using laser desorption/ionization mass spectrometry. Among them, cysteine-MOF was found to be a multifunctional composite as an excellent matrix and an efficient adsorbent for N -glycans due to its high hydrophilicity, low background interference and unique size-exclusion effect.