Destructive Upper Airway Disease from Eosinophilic Granulomatosis with Polyangiitis (EGPA): The Very First Case. (23rd May 2019)

• Record Type: Journal Article
• Authors: Saha, Biplab; Saha, Aditi; Cordeiro-Rudnisky, Fernanda; Shkolnik, Boris; Beegle, Scott
• Other Names: Soy Mehmet Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2019(2019)
• Publication Date: 2019-05-23
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2019/6173869
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystem vasculitic disorder that predominantly affects medium- and small-sized blood vessels. EGPA belongs to a group of vasculitides known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV). Upper airway involvement is seen in all ANCA-associated vasculitides, but destructive upper airway disease has never been reported in patients with EGPA. We report the first case of erosive chondritis and saddle nose deformity in a 50-year-old patient suffering from EGPA.