Primary pulmonary angiosarcoma: case reports and review of the literature. (June 2019)

• Record Type: Journal Article
• Authors: Virarkar, Mayur; Tayyab, Sidra; Thampy, Rajesh; Bhosale, Priya; Viswanathan, Chitra
• Is Part Of: Asian cardiovascular & thoracic annals. Volume 27:Number 5(2019)
• Page Start: 347
• Page End: 352
• Publication Date: 2019-06
• Subjects: Diagnosis -- differential -- hemangiosarcoma -- immunohistochemistry -- mediastinal neoplasms -- pulmonary artery -- vascular neoplasms; Heart -- Diseases -- Asia -- Periodicals; Heart -- Diseases -- Pacific Area -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Surgery -- Asia -- Periodicals; Heart -- Surgery -- Pacific Area -- Periodicals; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Asia -- Periodicals; Chest -- Surgery -- Pacific Area -- Periodicals; Chest -- Surgery -- Periodicals; 617.412
• DOI: 10.1177/0218492319836910
• Languages: English
• ISSNs: 0218-4923

Abstract

Pulmonary artery angiosarcoma is a rare malignant vascular tumor with an aggressive clinical course and a poor prognosis. Hemoptysis and shortness of breath have been reported as common clinical presentations. The exact clinicopathology is unknown. A tissue specimen obtained by percutaneous fine-needle aspiration cytology or open/thoracoscopic biopsy can confirm the diagnosis based on histopathological and immunohistochemical features. The differential diagnosis includes pulmonary thromboembolism, vascular malformations, and lung carcinoma. There is a paucity of literature describing this tumor, with only a few case reports available. There is also a lack of standardized guidelines for management, which further worsens the survival outcome. We report 3 cases of pulmonary artery angiosarcoma and review the recent literature.