Artificial Organelles: Nanomaterial‐Based Organelles Protect Normal Cells against Chemotherapy‐Induced Cytotoxicity (Adv. Mater. 27/2018). Issue 27 (2nd July 2018)

• Record Type: Journal Article
• Authors: Zhao, Ruibo; Liu, Xueyao; Yang, Xinyan; Jin, Biao; Shao, Changyu; Kang, Weijia; Tang, Ruikang
• Is Part Of: Advanced materials. Volume 30:Issue 27(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-07-02
• Subjects: artificial organelles -- chemotherapy -- cytotoxicity -- nanomaterials -- normal cells; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201870202
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Parallel to cellular organelles, artificial organelles based on nanomaterials are necessarily responsive to molecular cues and are biocompatible in a molecularly crowded cytoplasm. In article number1801304, Ruikang Tang and co‐workers present rationally designed nanomaterials of gold–oligonucleotides, which act as artificial organelles and conferr cell self‐defense in the threatening chemotherapeutic milieu. This intracellular implantation of functional artificial organelles into cells provides a novel and promising tactic for adjusting cell behavior and for manufacturing super cells.