Long-Term Follow-Up of Flexible Bronchoscopic Treatment for Bronchial Carcinoids with Curative Intent. (26th January 2010)

• Record Type: Journal Article
• Authors: Fuks, Leonardo; Fruchter, Oren; Amital, Anat; Fox, Benjamin D.; Abdel Rahman, Nader; Kramer, Mordechai R.
• Other Names: Novitsky Yuri Academic Editor.
• Is Part Of: Diagnostic and therapeutic endoscopy. Volume 2009(2009)
• Publication Date: 2010-01-26
• Subjects: Endoscopy -- Periodicals; Endoscopie; Endoscopy; Endoscopy -- Periodicals; Electronic journals; Periodicals; 616.07545
• DOI: 10.1155/2009/782961
• Languages: English
• ISSNs: 1070-3608

Abstract

Abstract : Background . Typical pulmonary carcinoids represent less than 5% of primary lung tumors. In patients with typical bronchial carcinoid, formal surgical resection still remains the gold-standard treatment. Data regarding long-term outcome in using flexible bronchoscope-based modalities under conscious sedation is very limited. Objectives . We sought to investigate, over extended follow-up period, the effectiveness of endobronchial resection for carcinoid tumors with curative intent using flexible bronchoscopy. Methods . Nd:YAG laser photoresection using flexible bronchoscope under conscious sedation. Follow-up included repeat bronchoscopy every 6 months and chest CT every year. Results . Ten patients aged 24 to 70 years with endobronchial carcinoid were treated. The tumor location was variable: 2 left Main bronchus, 1 left upper lobe bronchus, 2 right main bronchus, 2 right middle lobe bronchus and 3 right lower lobe bronchus. No major complications were observed. The patients required between 2 and 4 procedures. Patients were followed for a median period of 29 months with no evidence of tumor recurrence. Conclusions . Endobronchial laser photoresection of typical bronchial carcinoids using flexible bronchsocopy under conscious sedation is an effective treatment modality for a subgroup of patients that provides excellent long-term results that are similar to outcome obtained by more invasive procedures.