Cobalt(III)‐Catalyzed Allylation of Arene C–H Bonds. Issue 27 (20th July 2017)

• Record Type: Journal Article
• Authors: Ramachandran, Kuppan; Anbarasan, Pazhamalai
• Is Part Of: European journal of organic chemistry. Issue 27(2017)
• Page Start: 3965
• Page End: 3968
• Publication Date: 2017-07-20
• Subjects: Cobalt -- Allylation -- Nitrogen heterocycles -- Allylic compounds -- C–C coupling; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201700528
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The cobalt(III)‐catalyzed chelation‐assisted allylation of arene C–H bonds was accomplished by employing allyl carbonates. The important features of the present reaction include the use of directing groups such as pyrazoles and pyridines, wide functional‐group tolerance, and the synthesis of various allylated (hetero)arenes in good to excellent yields. On the basis of the observations, a plausible mechanism is also proposed involving the formation of a π‐allyl species. Abstract : An efficient protocol for the cobalt(III)‐catalyzed chelation‐assisted allylation of arene C–H bonds by employing allyl carbonates as allylating reagents and pyrazoles and pyridines as directing groups is described.