Benign paroxysmal positional vertigo in spontaneous intracranial hypotension. (3rd October 2018)

• Record Type: Journal Article
• Authors: Xia, Ping; Zhang, Si-Ran; Zhou, Zhi-Jie; Shao, Yu-Quan; Hu, Xing-Yue
• Is Part Of: Neurological research. Volume 40:Number 10(2018)
• Page Start: 868
• Page End: 873
• Publication Date: 2018-10-03
• Subjects: Spontaneous intracranial hypotension -- benign paroxysmal positional vertigo -- cerebrospinal fluid pressure; Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8005
• DOI: 10.1080/01616412.2018.1495883
• Languages: English
• ISSNs: 0161-6412

Abstract

ABSTRACT: Objectives : To assess the prevalence and related factors of benign paroxysmal positional vertigo (BPPV) in patients with spontaneous intracranial hypotension (SIH). Methods : We retrospectively reviewed 156 consecutive inpatients with SIH, and collected the clinical and radiological data. These patients were divided into BPPV group and non-BPPV group according to the clinical manifestation and the results of Dix-Hallpike or supine roll tests during hospitalization period. We performed a univariate analysis and a further multiple logistic regression analysis to identify the related factors of the development of BPPV in SIH patients. Results : BPPV was detected in 18 patients among the total 156 SIH patients (11.54%). The univariate analysis showed a low cerebrospinal fluid (CSF) pressure ( P = 0.018), a small pontomesencephalic angle ( P = 0.012) and a positive venous distension sign (VDS) ( P = 0.045) were associated with the presence of BPPV. But the multivariate analysis only demonstrated a low CSF pressure was related to the presence of BPPV (OR = 1.022, 95% CI: 1.001–1.043, P = 0.044). Conclusion : BPPV is common in SIH patients. SIH patients with low CSF pressure may be prone to develop BPPV.