Catalytic Enantioselective 1, 3‐Alkyl Shift in Alkyl Aryl Ethers: Efficient Synthesis of Optically Active 3, 3′‐Diaryloxindoles. (20th April 2018)
- Record Type:
- Journal Article
- Title:
- Catalytic Enantioselective 1, 3‐Alkyl Shift in Alkyl Aryl Ethers: Efficient Synthesis of Optically Active 3, 3′‐Diaryloxindoles. (20th April 2018)
- Main Title:
- Catalytic Enantioselective 1, 3‐Alkyl Shift in Alkyl Aryl Ethers: Efficient Synthesis of Optically Active 3, 3′‐Diaryloxindoles
- Authors:
- Gade, Amol B.
Bagle, Pradip N.
Shinde, Popat S.
Bhardwaj, Vipin
Banerjee, Subhrashis
Chande, Ajit
Patil, Nitin T. - Abstract:
- Abstract: Reported is the first organocatalytic asymmetric 1, 3‐alkyl shift in alkyl aryl ethers for the synthesis of chiral 3, 3′‐diaryloxindoles using a chiral Brønsted acid catalyst. Preliminary results showed that each enantiomer of the 3, 3′‐diaryloxindole, and a racemic mixture, showed different antiproliferative activities against HeLa cell lines by using an MTT assay.
- Is Part Of:
- Angewandte Chemie. Volume 130:Number 20(2018)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 130:Number 20(2018)
- Issue Display:
- Volume 130, Issue 20 (2018)
- Year:
- 2018
- Volume:
- 130
- Issue:
- 20
- Issue Sort Value:
- 2018-0130-0020-0000
- Page Start:
- 5837
- Page End:
- 5841
- Publication Date:
- 2018-04-20
- Subjects:
- Brønsted-Säuren -- Heterocyclen -- Organokatalyse -- Umlagerungen -- Synthesemethoden
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201801650 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10782.xml