Accessing Frustrated Lewis Pair Chemistry from a Spectroscopically Stable and Classical Lewis Acid‐Base Adduct. Issue 20 (17th April 2018)

• Record Type: Journal Article
• Authors: Johnstone, Timothy C.; Wee, Gabriel N. J. H.; Stephan, Douglas W.
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 20(2018)
• Page Start: 5881
• Page End: 5884
• Publication Date: 2018-04-17
• Subjects: borane -- frustrated Lewis pairs -- NMR spectroscopy -- proazaphosphatrane -- X-ray diffraction; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201802385
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: B(C6 F5 )3 and P(MeNCH2 CH2 )3 N form a classical Lewis adduct, (C6 F5 )3 BP(MeNCH2 CH2 )3 N. Although (C6 F5 )3 BP(MeNCH2 CH2 )3 N does not exhibit spectroscopic evidence of dissociation into its constituent acid and base, products of frustrated Lewis pair (FLP) addition reactions are seen with PhNCO, PhCH2 N3, PhNSO, and CO2 . Computational studies show that thermal access to the dissociated acid and base permits FLP reactivity to proceed. These results demonstrate that FLP reactivity extends across the entire continuum of equilibria governing Lewis acid‐base adducts. Abstract : From the other side : A strong Lewis adduct undergoes frustrated Lewis pair (FLP) addition despite the inability to spectroscopically observe the dissociated acid and base. The importance of investigating apparently stable Lewis adducts for FLP reactivity is highlighted.