Miniaturized-electroneurostimulators and self-powered/rechargeable implanted devices for electrical-stimulation therapy. (March 2018)

• Record Type: Journal Article
• Authors: Reddy, Sathish; He, Liumin; Ramakrishana, Seeram
• Is Part Of: Biomedical signal processing and control. Volume 41(2018)
• Page Start: 255
• Page End: 263
• Publication Date: 2018-03
• Subjects: Miniaturized-electroneurostimulators -- Electroceuticals -- Neurostimulations -- Self-powered implantable device -- Rechargeable implantable device; Signal processing -- Periodicals; Biomedical engineering -- Periodicals; Signal Processing, Computer-Assisted -- Periodicals; Image Processing, Computer-Assisted -- Periodicals; Biomedical Engineering -- Periodicals; 610.28
• DOI: 10.1016/j.bspc.2017.11.018
• Languages: English
• ISSNs: 1746-8094

Abstract

Abstract: Advances in technology provide a path towards a new type of medicine that allows physicians to treat diseases with electricity rather than drugs. Recently, miniaturized-electroneurostimulators or electroceuticals which employ electrical-stimulation to affect and modify functions of the body have been attracting great attention. Since the nervous system is criss-crossing in our body to control many aspects of our organ function, bioelectronic implants can treat disease by stimulating nerves as an alternative to drugs. Miniaturized-electroneurostimulators provides a more-targeted approach to treat illness and alleviate pain, presenting a lucrative opportunity. In this review, we discussed on basic concept of electroceuticals or miniaturized-electroneurostimulators, electrical-neurostimulators and electrical-neurostimulation parameters such as amplitude, pulse width, pulse rate, electrode configuration and impedance. Importantly, we focus on self-powered/rechargeable implantable devices which are essential to avoid unnecessary infection or bleeding during repeated surgery. In addition, we summarized on self-powered artificial cardiac pacemaker, self-powered wound dressing, externally-powered dust，externally-powered implantable drug delivery device, wireless charging system in implanted tiny pacemaker, for treatment of diseases by electrical-stimulation and listed potential risks of implanted electrical-neurostimulation device. Miniaturized-electroneurostimulators are expected to play a profound role in implantable neural small devices that treat illnesses and support restore functions in injured or disabled nervous system and also used for monitoring the vital signs of a person.