Bioinspired 3D printable pectin-nanocellulose ink formulations. (15th September 2019)

• Record Type: Journal Article
• Authors: Cernencu, Alexandra I.; Lungu, Adriana; Stancu, Izabela-Cristina; Serafim, Andrada; Heggset, Ellinor; Syverud, Kristin; Iovu, Horia
• Is Part Of: Carbohydrate polymers. Volume 220(2019)
• Page Start: 12
• Page End: 21
• Publication Date: 2019-09-15
• Subjects: 3D printing -- Polysaccharide -- Hydrogels -- Pectin -- Cellulose nanofibrils; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2019.05.026
• Languages: English
• ISSNs: 0144-8617

Abstract

Graphical abstract: Highlights: Bio-based inks comprising nanocellulose and pectin were assessed for 3D printing. The shear-thinning properties of carboxylated cellulose nanofibrils were exploited. The ability of low methoxy-pectin to be fast crosslinked with Ca 2+ was valued. The newly developed inks could be appealing as platforms for tissue engineering. Abstract: The assessment of several ink formulations for 3D printing based on two natural macromolecular compounds is presented. In the current research we have exploited the fast crosslinking potential of pectin and the remarkable shear-thinning properties of carboxylated cellulose nanofibrils, which is known to induce a desired viscoelastic behavior. Prior to 3D printing, the viscoelastic properties of the polysaccharide inks were evaluated by rheological measurements and injectability tests. The reliance of the printing parameters on the ink composition was established through one-dimensional lines printing, the base units of 3D-structures. The performance of the 3D-printed structures after ionic cross-linking was evaluated in terms of mechanical properties and rehydration behavior. MicroCT was also used to evaluate the morphology of the 3D-printed objects regarding the effect of pectin/nanocellulose ratio on the geometrical features of scaffolds. The proportionality between the two polymers proved to be the determining factor for the firmness and strength of the printed objects.