White matter lesions and sudden sensorineural hearing loss. (July 2019)

• Record Type: Journal Article
• Authors: Ciorba, Andrea; Bianchini, Chiara; Crema, Laura; Ceruti, Stefano; Ermili, Francesca; Aimoni, Claudia; Pelucchi, Stefano
• Is Part Of: Journal of clinical neuroscience. Volume 65(2019)
• Page Start: 6
• Page End: 10
• Publication Date: 2019-07
• Subjects: White matter lesions -- WMLs -- Sudden sensorineural hearing loss -- SSNHL -- Hearing recovery; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2019.04.037
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: This is the first clinical study evaluating the role of WMLs in subjects affected by SSNHL. Cerebral MRI, usually performed in all SSNHL patients, could also have a prognostic role in the management of SSNHL. According to the results of this study, the presence of WMLs can be linked to a poorer hearing recovery rate. Abstract: Aim of this paper is to investigate the presence of White Matter Lesions (WMLs) in subjects affected by Sudden Sensorineural Hearing Loss (SSNHL) and possibly to evaluate the significance of WMLs in SSNHL patients. A total of 64 patients (cases) affected by SSNHL were included in this case-control study. Hearing tests were performed at SSNHL onset, after 7 days and after 30 days. Cerebral MRI sequences were performed to rule out retrocochlear pathology, and WMLs were evaluated if present. MRI control group included 32 subjects, without hearing loss, affected by pituitary adenoma, who underwent cerebral MRI of follow-up. WML presence in those affected by SSNHL resulted having a similar distribution to that of the control group; however, we observed complete hearing recovery in 42, 9% of patients without WML and in 11, 6% of patients with WML >1 (p = 0, 017 * ). The incidence of WML in patients with SSNHL was not different compared to that of the control group; however, MRI could have a prognostic role for SSNHL patients, as the presence of WMLs can been linked to a poorer hearing recovery rate.