A Solid Iridium Catalyst for Diastereoselective Hydrogenation. Issue 64 (25th October 2017)

• Record Type: Journal Article
• Authors: Romanenko, Iuliia; Jaffeux, Louis; Veyre, Laurent; Lacôte, Emmanuel; Meille, Valérie; Thieuleux, Chloé
• Is Part Of: Chemistry. Volume 23:Issue 64(2017)
• Page Start: 16171
• Page End: 16173
• Publication Date: 2017-10-25
• Subjects: diastereoselective hydrogenation -- heterogenized complex -- hybrid catalysts -- iridium -- supported catalysts; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201703872
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: An Ir(NHC) supported catalyst is used in the selective hydrogenation of terpinen‐4‐ol to cis p ‐menthan‐4‐ol. Its activity, selectivity and stability are compared to those of a homogeneous homologue [IrCl(COD)MesImPr] and to a commercial Pd/C. The solid Ir catalyst is much more selective than the Pd catalyst (92 vs. 42 % at 80 °C) but also more active, more selective and more stable than the iridium complex in solution. For the first time, a supported catalyst shows an enhanced activity with respect to a complex in a diastereoselective hydrogenation reaction. Abstract : Cool cat : An Ir(NHC)‐based hybrid material is used in a diastereoselective hydrogenation. It selectively hydrogenates terpinen‐4‐ol to cis p‐menthan‐4‐ol. It is much more selective than a commercial Pd/C catalyst. It is more active, selective and stable than the homogeneous homologue in solution.