(1→3)-β-D-glucanemia in deep mycosis. Issue 4 (1997)

• Record Type: Journal Article
• Authors: Obayashi Obayashi, Taminori Taminori
• Is Part Of: Mediators of inflammation. Volume 6:Issue 4(1997)
• Page Start: 271
• Page End: 273
• Publication Date: 1997
• Subjects: Inflammation -- Mediators -- Periodicals; Biological response modifiers -- Periodicals; Inflammation (Pathologie) -- Médiateurs; Immunomodulateurs; Biological response modifiers; Inflammation -- Mediators; Immunology; Autacoids; Immunologic Factors; Cell Adhesion Molecules; Cell Communication; Cytokines; Inflammation; Periodicals; Electronic journals; 616.0473
• DOI: 10.1080/09629359791604
• Languages: English
• ISSNs: 0962-9351

Abstract

Abstract : Factor G, a coagulation proenzyme of the Japanese horseshoe crab ( Tachypleus tridentatus ), is extremely sensitive to (1→3)-β-D-glucan, which is a characteristic cell-wall constituent of fungi. Using this factor and by a digestion study with (1→3)-β-D-glucan, we showed that blood from patients with deep m ycosis contains the glucan. It was detected in 39 out of 41 fungal febrile episodes (sensitivity 90%), but in none of the 59 nonfungal febrile episodes (specificity 100%).