Real-time transthoracic vector flow imaging of the heart in pediatric patients. (June 2019)

• Record Type: Journal Article
• Authors: Collins II, R. Thomas; Laughlin, Megan E.; Lang, Sean M.; Bolin, Elijah H.; Daily, Joshua A.; Jensen, Hanna A.; Jensen, Morten O.
• Is Part Of: Progress in pediatric cardiology. Volume 53(2019)
• Page Start: 28
• Page End: 36
• Publication Date: 2019-06
• Subjects: Transthoracic echocardiography -- Congenital heart disease -- Velocity flow -- Vector flow imaging; Pediatric cardiology -- Periodicals; Cardiovascular Diseases -- Periodicals; Infant; Child; Cardiologie pédiatrique -- Périodiques; 618.9212005
• DOI: 10.1016/j.ppedcard.2019.02.003
• Languages: English
• ISSNs: 1058-9813

Abstract

Abstract: In children with congenital heart defects, Doppler ultrasound is the standard, bedside imaging modality. However, precise characterization of blood flow is challenging due to angle-dependent and one-dimensional velocity estimation. Contrast agent free Vector Flow Imaging is a new ultrasound technology that enables angle-independent visualization of the detailed flow field. Two piglets, one with normal cardiac anatomy and one with congenital heart disease comprised of valvular pulmonary stenosis, a dilated main pulmonary artery, and an incomplete atrioventricular canal defect, were imaged transthoracically and epicardially using a BK Ultrasound bk5000 with built-in vector flow imaging and a 5 MHz linear probe. Subsequently, two children, one with normal cardiac anatomy and one with congenital heart disease comprised of aortic valve stenosis and coarctation of the aorta were imaged transthoracically. Transthoracic two-dimensional echocardiography and vector flow imaging were readily performed in both animals and were limited only by the geometry of the porcine thorax. In addition, transthoracic vector flow imaging was successfully performed in both children, and abnormal flow secondary to cardiac anomalies was visible. Adequate penetration was obtained to a depth of 6.5 cm. Our group has previously demonstrated for the first time that transthoracic vector flow imaging echocardiography is feasible and practicable in pediatric-sized patients, and this paper describes examples of these concepts and in-depth comparisons with traditional imaging modalities. This paper demonstrates that commercially available vector flow imaging technology can be utilized in pediatric cardiac applications as a bedside transthoracic imaging modality, providing advanced detail of blood flow patterns within the cardiac chambers, across valves, and in the great arteries. Highlights: Vector Flow Imaging (VFI), a new, ultrasound-based imaging method, provides real-time, angle-independent flow visualization. VFI is non-invasive and provides advanced hemodynamic flow assessment along with bedside availability and mobility. This is the first report demonstrating transthoracic VFI is feasible and practicable in pediatric-sized piglets and children.