Relative Risk Chart Score for the Assessment of the Cardiovascular Risk in Young Patients with Ankylosing Spondylitis. (15th February 2018)

• Record Type: Journal Article
• Authors: Rueda-Gotor, Javier; Genre, Fernanda; Corrales, Alfonso; Blanco, Ricardo; Fuentevilla, Patricia; Portilla, Virginia; Expósito, Rosa; Arnaiz, Cristina Mata; Pina, Trinitario; González-Juanatey, Carlos; Rodriguez-Rodriguez, Luis; González-Gay, Miguel A.
• Other Names: Rothschild Bruce M. Academic Editor.
• Is Part Of: International journal of rheumatology. Volume 2018(2018)
• Publication Date: 2018-02-15
• Subjects: Rheumatology -- Periodicals; Rheumatology; Rheumatology; Electronic journals; Periodicals; Periodicals; 616.723
• DOI: 10.1155/2018/1847894
• Languages: English
• ISSNs: 1687-9260

Abstract

Abstract : Objective . To determine if the use of the relative risk (RR) chart score may help to identify young ankylosing spondylitis (AS) patients at high risk of cardiovascular (CV) disease. Methods . 73 AS patients younger than 50 years were assessed. CV risk was calculated according to the total cholesterol systematic coronary risk evaluation (TC-SCORE) and the RR chart score. C-reactive protein (CRP) value at disease diagnosis and carotid ultrasound data were also analyzed. Results . Twenty (27.4%) patients exhibited carotid plaques being classified into the category of very high CV risk. None of them was found to have a high/very high TC-SCORE. CRP > 3 mg/L at disease diagnosis was associated with the presence of carotid plaques (odds ratio 5.66, p = 0.03 ). Whereas only 5 (14.2%) of the 35 patients with RR = 1 had carotid plaques, 15 (39.5%) of 38 with RR > 1 showed plaques. A model that included the performance of carotid US in patients with RR > 1 who had CRP > 3 mg/L allowed us to identify 60% of very high risk patients, with a specificity of 77.4%. Conclusions . RR chart score assessment may help to identify young AS patients at high risk of CV disease.