Ibuprofen for Ductus Arteriosus Months after Birth. (14th June 2016)

• Record Type: Journal Article
• Authors: Frauenfelder, Odile; van Beynum, Ingrid M.; Reiss, Irwin K. M.; Simons, Sinno H. P.
• Other Names: Muraskas Jonathan Academic Editor.
• Is Part Of: Case reports in pediatrics. Volume 2016(2016)
• Publication Date: 2016-06-14
• Subjects: Pediatrics -- Periodicals; Pediatrics; Pediatrics; Electronic journals; Periodicals; Case Reports; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 618.92
• DOI: 10.1155/2016/2659389
• Languages: English
• ISSNs: 2090-6803

Abstract

Abstract : Ibuprofen is a well-known agent used to treat patent ductus arteriosus in preterm neonates in the first days of life. In the current case report we illustrate the potential use of ibuprofen in two preterm neonates 60 and 88 days after birth, respectively. To our knowledge, this is the first report on the effects of ibuprofen on patent ductus arteriosus in preterm newborns after months of life. These cases suggest that the ductus arteriosus does not become refractory for ibuprofen after the first days of life. Late closure of the duct with ibuprofen might still improve the cardiorespiratory condition and prevent infants from surgical closure. Controlled trials are necessary to further study these findings.