Commitment Isn't for Everyone. Issue 6 (June 2019)

• Record Type: Journal Article
• Authors: Josling, Gabrielle A.; Llinás, Manuel
• Is Part Of: Trends in parasitology. Volume 35:Issue 6(2019)
• Page Start: 381
• Page End: 383
• Publication Date: 2019-06
• Subjects: Plasmodium falciparum -- malaria -- gametocyte -- commitment -- sexual stage; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2019.03.012
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract : The majority of malaria parasites during human infection are asexual and are unable to be transmitted to mosquitoes. Only sexually differentiated parasites (gametocytes) can be successfully transmitted to complete the lifecycle. In a recent study by Bancells et al . ( Nat. Microbiol. 2019;4:144–154), a new route of sexual conversion is identified that does not require a prior round of replication.