An acute transverse myelitis attack after autologous stem cell transplantation: A rare case. (June 2019)

• Record Type: Journal Article
• Authors: Cömert, Pınar; Albayrak, Murat; Yıldız, Abdulkerim; Şahin, Osman; Öztürk, Çiğdem Pala; Maral, Senem; Güneş, Gürsel; Afacan Öztürk, Hacer Berna; Sağlam, Buğra
• Is Part Of: Transfusion and apheresis science. Volume 58:Number 3(2019)
• Page Start: 341
• Page End: 343
• Publication Date: 2019-06
• Subjects: Autologous stem cell transplantation -- Neurological complication -- Transverse myelitis; Blood -- Transfusion -- Periodicals; Hemapheresis -- Periodicals; 615.39
• DOI: 10.1016/j.transci.2019.05.002
• Languages: English
• ISSNs: 1473-0502

Abstract

Abstract: Transverse myelitis is a quite rare complication of hematopoietic stem cell transplantation. The case is here reported of a 49 year old male with diffuse large B cell lymphoma in complete remission who developed transverse myelitis after autologous stem cell transplantation. The patient presented with numbness and sensory loss of the bilateral lower extremities and difficulty in urinating on the 20th day after cell transplantation. Millimetric hyperintensity was detected in the C5-C6 and T2-T5 segments of the spinal cord on cervical and thoracic vertebral magnetic resonance imaging. Treatment was initiated of pulse steroid and intravenous immunoglubulin followed by plasmapheresis and cyclophosphamide due to inadequate response. The patient then started a rehabilitation program and was discharged in the 9th month after stem cell transplantation when most of the symptoms were relieved. To the best of our knowledge, this is the first case reported in literature of TM development after autologous stem cell transplantation.