Optimal vaccination and control strategies against dengue. (16th April 2019)

• Record Type: Journal Article
• Authors: Fischer, Anne; Chudej, Kurt; Pesch, Hans Josef
• Is Part Of: Mathematical methods in the applied sciences. Volume 42:Number 10(2019)
• Page Start: 3496
• Page End: 3507
• Publication Date: 2019-04-16
• Subjects: Asian tiger mosquito -- dengue -- insecticide -- non‐linear programming -- optimal control -- vaccination; Mathematics -- Periodicals; Technology -- Mathematics -- Periodicals; 519
• DOI: 10.1002/mma.5594
• Languages: English
• ISSNs: 0170-4214

Abstract

Abstract : This article focuses on the mathematical modelling of a disease outbreak of dengue fever. A cost‐efficient fighting strategy, which simultaneously uses vaccination, application of insecticides to adult and aquatic mosquitoes, and an approach to decrease the number of man‐made breeding places for the mosquitoes, is computed using optimal control. Vaccination includes a paediatric vaccination and an imperfect random mass vaccination with waning immunity.