Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges. (12th July 2018)

• Record Type: Journal Article
• Authors: Aridi, Tarek; Fawwaz, Mohamad; Kassab, Ahmad; Bahmad, Marwan; Houcheimi, Faisal; Mshiek, Mohamad; Boulos, Fouad; Kanj, Ali; Ramadan, Ghassan; Bahmad, Hisham F.; Fakhruddin, Najla
• Other Names: Colombo Piergiuseppe Academic Editor.
• Is Part Of: Case reports in surgery. Volume 2018(2018)
• Publication Date: 2018-07-12
• Subjects: Surgery -- Periodicals; Surgery -- Case studies -- Periodicals; Surgical Procedures, Operative; General Surgery; Surgery; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 617
• DOI: 10.1155/2018/8240534
• Languages: English
• ISSNs: 2090-6900

Abstract

Abstract : Lymphoepithelioma-like carcinoma (LELC) of the breast is an extremely rare tumor type. Histologically, it mimics undifferentiated nasopharyngeal carcinoma by demonstrating nests of neoplastic epithelial cells in a background of lymphoplasmacytic infiltrates. This paper reports a 62-year-old female patient with a 3 × 1.5 cm BI-RADS type IV breast mass diagnosed on excisional biopsy as LELC. The tumor is negative for estrogen and progesterone receptors and did not overexpress HER2/neu. Routine tests for clearance before surgery were performed, and patient was managed by a modified radical mastectomy with axillary lymph node dissection showing no residual tumor. Surgical CAse REports (SCARE) guidelines were followed for reporting our case. The rarity of LELC of the breast warrants the establishment and implementation of well-defined guidelines and criteria for diagnosis and management.