Moderate-Intensity Exercise Improves Body Composition and Improves Physiological Markers of Stress in HIV-Infected Men. (11th December 2012)

• Record Type: Journal Article
• Authors: Dudgeon, Wesley David; Jaggers, Jason Reed; Phillips, Kenneth Doyle; Durstine, John Larry; Burgess, Stephanie E.; Lyerly, George William; Davis, John Mark; Hand, Gregory Alan
• Other Names: Aunis D. Academic Editor.; Machado R. L. D. Academic Editor.; Poudrier J. Academic Editor.
• Is Part Of: ISRN AIDS. Volume 2012(2012)
• Publication Date: 2012-12-11
• Subjects: AIDS (Disease) -- Periodicals; Acquired Immunodeficiency Syndrome; AIDS (Disease); Periodical; Electronic journals; Periodicals; 616.9792
• DOI: 10.5402/2012/145127
• Languages: English
• ISSNs: 2090-939X

Abstract

Abstract : HIV/AIDS and its treatment often alter body composition and result in poorer physical functioning. The aim of this study was to determine the effects of a moderate-intensity exercise program on body composition and the hormones and cytokines associated with adverse health outcomes. HIV-infected males (N = 111 ) were randomized to an exercise group (EX) who completed 6 weeks of moderate-intensity exercise training, or to a nonintervention control group (CON). In pre- and postintervention, body composition was estimated via DXA, peak strength was assessed, and resting blood samples were obtained. There was a decrease in salivary cortisol at wake (P = 0.025 ) in the EX and a trend (P = 0.07 ) for a decrease 1 hour after waking. The EX had a significant increase in lean tissue mass (LTM) (P < 0.001 ) following the intervention. Those in the EX below median body fat (20%) increased LTM (P = 0.014 ) only, while those above 20% decreased fat mass (P = 0.02 ), total fat (N = 0.009 ), and trunk fat (P = 0.001 ), while also increasing LTM (P = 0.027 ). Peak strength increased between 14% and 28% on all exercises in the EX group. These data indicate that 6 weeks of moderate-intensity exercise training can decrease salivary cortisol levels, improve physical performance, and improve body composition in HIV-infected men.