Plasma 25-Hydroxyvitamin D Is Independently Associated with Hemoglobin Concentration in Male Subjects with Type 2 Diabetes Mellitus. (26th May 2011)

• Record Type: Journal Article
• Authors: Meguro, Shu; Tomita, Masuomi; Katsuki, Takeshi; Kato, Kiyoe; Oh, Henpiru; Ainai, Akira; Ito, Ryo; Takeda, Shu; Kawai, Toshihide; Atsumi, Yoshihito; Itoh, Hiroshi; Hasegawa, Hideki
• Other Names: Tangpricha Vin Academic Editor.
• Is Part Of: International journal of endocrinology. Volume 2011(2011)
• Publication Date: 2011-05-26
• Subjects: Endocrinology -- Periodicals; Endocrinology; Endocrinology -- Periodicals; Endocrine System Diseases -- Periodicals; Periodicals; 616.4
• DOI: 10.1155/2011/362981
• Languages: English
• ISSNs: 1687-8337

Abstract

Abstract : Introduction . It was reported that 25-hydroxyvitamin D level was independently associated with anemia in chronic kidney diseases, but the relation between vitamin D and anemia in diabetes mellitus is not still certain. We analyzed the relation between plasma 25-hydroxyvitamin D level and hemoglobin concentration. Materials and Methods . A cross-sectional study in male patients with type 2 diabetes was performed. Correlation coefficients and standardized partial regression coefficient for the hemoglobin concentration were evaluated. Results . Hemoglobin concentration was positively correlated with body mass index, HbA1c, estimated glomerular filtration rate, cholinesterase, and 25-hydroxyvitamin D level and negatively correlated with age, duration of diabetes mellitus, serum creatinine, and urinary albumin creatinine ratio. Multiple regression analysis revealed the independent relation of 25-hydroxyvitamin D to hemoglobin concentration. Conclusions . Plasma circulating form of vitamin D is significantly associated with hemoglobin concentration in diabetes mellitus independent of the clinical markers for kidney function or nutrition.