Flexible and Stretchable PEDOT‐Embedded Hybrid Substrates for Bioengineering and Sensory Applications. Issue 6 (13th May 2019)

• Record Type: Journal Article
• Authors: Fallahi, Afsoon; Mandla, Serena; Kerr‐Phillip, Thomas; Seo, Jungmok; Rodrigues, Raquel O.; Jodat, Yasamin A.; Samanipour, Roya; Hussain, Mohammad Asif; Lee, Chang Kee; Bae, Hojae; Khademhosseini, Ali; Travas‐Sejdic, Jadranka; Shin, Su Ryon
• Is Part Of: ChemNanoMat. Volume 5:Issue 6(2019)
• Page Start: 729
• Page End: 737
• Publication Date: 2019-05-13
• Subjects: poly(3, 4-ethylene dioxythiophene) -- stretchable -- electrochemical polymerization -- electrospinning -- cardiac tissue engineering -- flexible electronics; Nanochemistry -- Periodicals; Nanostructured materials -- Periodicals; Nanochemistry; Nanostructured materials; Periodicals; 541.2
• DOI: 10.1002/cnma.201900146
• Languages: English
• ISSNs: 2199-692X

Abstract

Abstract: Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3, 4‐ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics. Abstract : Flexible and stretchable PEDOT‐embedded hybrid electrospun mats with tunable fiber orientation showed anisotropic elastomeric mechanical properties and high electrical conductivity along with high cellular viability that could serve as biocompatible strain sensors for monitoring muscle contraction and body movement.