Assessment of fat-free mass from bioelectrical impedance analysis in men and women with Prader-Willi syndrome: cross-sectional study. (4th July 2019)

• Record Type: Journal Article
• Authors: Bedogni, Giorgio; Grugni, Graziano; Tringali, Gabriella; Tamini, Sofia; Marzullo, Paolo; Sartorio, Alessandro
• Is Part Of: International journal of food sciences and nutrition. Volume 70:Number 5(2019)
• Page Start: 645
• Page End: 649
• Publication Date: 2019-07-04
• Subjects: Bioelectrical impedance analysis -- body composition -- dual energy X-ray absorptiometry -- Prader-Willi syndrome -- prediction equations; Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.1080/09637486.2018.1554623
• Languages: English
• ISSNs: 0963-7486

Abstract

Abstract: We have recently shown that population-specific formulae are required to estimate fat-free mass (FFM) from bioelectrical impedance analysis (BIA) in obese women with Prader-Willi syndrome (PWS) matched by age and percent fat mass (FM) to non-PWS women. The present cross-sectional study was aimed at developing generalised BIA equations that could be used in PWS subjects independently of sex and FM. We used dual-energy X-ray absorptiometry to measure FFM and BIA to measure whole-body impedance at 50 kHz (Z50 ) in 34 women and 21 men with PWS. The impedance index, that is, height (cm) 2 /Z50 (Ω), explained 77% (BCa-bootstrapped 95% CI 65 to 85%) of the variance of FFM with a root mean squared error of the estimate of 3.7 kg (BCa-bootstrapped 95% CI 3.2 to 4.5 kg). BIA can be used to estimate FFM in obese and non-obese PWS men and women by means of population-specific equations.