Choroidal Metastasis of Non-Small Cell Lung Cancer That Responded to Gefitinib. (11th September 2013)

• Record Type: Journal Article
• Authors: Shimomura, Iwao; Tada, Yuji; Miura, Gen; Suzuki, Toshio; Matsumura, Takuma; Tsushima, Kenji; Terada, Jiro; Kurimoto, Ryota; Sakaida, Emiko; Sekine, Ikuo; Takiguchi, Yuichi; Yamamoto, Shuichi; Tatsumi, Koichiro
• Other Names: Bialasiewicz A. A. Academic Editor.; Chen H. Y. Academic Editor.; Fuse N. Academic Editor.; Rosner M. Academic Editor.
• Is Part Of: Case reports in ophthalmological medicine. Volume 2013(2013)
• Publication Date: 2013-09-11
• Subjects: Ophthalmology -- Periodicals; Eye -- Diseases -- Periodicals; Ophthalmology; Eye Diseases; Eye -- Diseases; Ophthalmology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 617.7
• DOI: 10.1155/2013/213124
• Languages: English
• ISSNs: 2090-6722

Abstract

Abstract : A 52-year-old Japanese woman presented with optical symptoms, including left-sided myodesopsia, blurred vision, narrowed visual field, and diminished visual acuity. Ocular evaluation revealed a metastatic tumor in the choroid. Further examinations identified pulmonary adenocarcinoma as the primary tumor. Because an epidermal growth factor receptor gene ( EGFR ) mutation was detected in a biopsy specimen, gefitinib treatment was initiated. Dramatic responses were obtained in the primary tumor and metastatic foci. Optical symptoms improved and remained stable for 5 months during the treatment, until relapse. This report demonstrates that gefitinib is effective for choroidal metastasis of pulmonary adenocarcinoma harboring an EGFR mutation.