HomoKinase: A Curated Database of Human Protein Kinases. (22nd April 2013)

• Record Type: Journal Article
• Authors: Subramani, Suresh; Jayapalan, Saranya; Kalpana, Raja; Natarajan, Jeyakumar
• Other Names: Colonna G. Academic Editor.; Fanelli F. Academic Editor.
• Is Part Of: ISRN computational biology. Volume 2013(2013)
• Publication Date: 2013-04-22
• Subjects: Computational biology -- Periodicals; Computational biology; Electronic journals; Periodicals; 570.285
• DOI: 10.1155/2013/417634
• Languages: English
• ISSNs: 2314-5420

Abstract

Abstract : HomoKinase database is a comprehensive collection of curated human protein kinases and their relevant biological information. The entries in the database are curated by three criteria: HGNC approval, gene ontology-based biological process (protein phosphorylation), and molecular function (ATP binding and kinase activity). For a given query protein kinase name, the database provides its official symbol, full name, other known aliases, amino acid sequences, functional domain, gene ontology, pathways assignments, and drug compounds. In addition, as a search tool, it enables the retrieval of similar protein kinases with specific family, subfamily, group, and domain combinations and tabulates the information. The present version contains 498 curated human protein kinases and links to other popular databases.