An Active Palladium Colloidal Catalyst for the Selective Oxidative Heterocoupling of (Hetero)Aryl Boronic Acids. Issue 17 (15th May 2018)

• Record Type: Journal Article
• Authors: Sable, Vaibhav; Maindan, Karan; Bhilare, Shatrughn; Chrysochos, Nicolas; Schulzke, Carola; Kapdi, Anant R.
• Is Part Of: Chemistry, an Asian journal. Volume 13:Issue 17(2018)
• Page Start: 2489
• Page End: 2498
• Publication Date: 2018-05-15
• Subjects: boronic acids -- heterocoupling -- one-pot synthesis -- palladium colloids -- tandem reactions; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201800358
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract: A highly selective oxidative heterocoupling protocol for (hetero)aryl boronic acids with an active palladium colloidal catalyst was developed. The judicious choice of electronically different aryl boronic acids made possible such couplings under mild conditions, with air as oxidant, while embracing a wide substrate scope. This successful approach further allowed the development of a unique one‐pot sequential oxidative heterocoupling/Suzuki–Miyaura cross‐coupling tandem process for accessing substituted terphenyls. Abstract : Heterocoupling of (hetero)aryl boronic acids : A highly selective oxidative heterocoupling protocol for (hetero)aryl boronic acids with an active palladium colloidal catalyst was developed. The judicious choice of electronically different aryl boronic acids allowed the development of a unique one‐pot sequential oxidative heterocoupling/Suzuki–Miyaura cross‐coupling tandem process for accessing substituted terphenyls under mild conditions.