The role of the vaginal microbiome in gynaecological cancer. (12th April 2017)

• Record Type: Journal Article
• Authors: Champer, M; Wong, AM; Champer, J; Brito, IL; Messer, PW; Hou, JY; Wright, JD
• Is Part Of: BJOG. Volume 125:Number 3(2018)
• Page Start: 309
• Page End: 315
• Publication Date: 2017-04-12
• Subjects: Cervical cancer -- cervical intraepithelial neoplasia -- human papillomavirus -- Lactobacillus -- probiotics -- vaginal microbiome; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618
• DOI: 10.1111/1471-0528.14631
• Languages: English
• ISSNs: 1470-0328

Abstract

Abstract : Human microbiome research has shown commensal bacteria to be a major factor in both wellness and disease pathogenesis. Interest in the microbiome has recently expanded beyond the gut to include a multitude of other organ systems for which the microbiome may have health implications. Here, we review the role of the vaginal microbiome in health and disease, with a particular focus on gynaecologic malignancies. Further, we suggest that it may be possible to expand the use of probiotics in the treatment of gynaecological cancers. Tweetable abstract: A review of the research to date on the relation between the vaginal microbiome and gynaecological cancers. Tweetable abstract: A review of the research to date on the relation between the vaginal microbiome and gynaecological cancers.