Radical Cyclization of Alkene‐Tethered Ketones Initiated by Hydrogen‐Atom Transfer. (4th December 2017)
- Record Type:
- Journal Article
- Title:
- Radical Cyclization of Alkene‐Tethered Ketones Initiated by Hydrogen‐Atom Transfer. (4th December 2017)
- Main Title:
- Radical Cyclization of Alkene‐Tethered Ketones Initiated by Hydrogen‐Atom Transfer
- Authors:
- Saladrigas, Mar
Bosch, Caroline
Saborit, Gisela V.
Bonjoch, Josep
Bradshaw, Ben - Abstract:
- Abstract: An unprecedented C−C coupling reaction between alkenes and ketones by hydrogen‐atom transfer, using Fe(acac)3 and PhSiH3 in EtOH, is described. This mild protocol features high site selectivity and allows the construction of sterically congested structures containing tertiary alcohols and quaternary centers. The overall process introduces a novel strategic bond disconnection for ring‐closing reactions.
- Is Part Of:
- Angewandte Chemie. Volume 130:Number 1(2018)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 130:Number 1(2018)
- Issue Display:
- Volume 130, Issue 1 (2018)
- Year:
- 2018
- Volume:
- 130
- Issue:
- 1
- Issue Sort Value:
- 2018-0130-0001-0000
- Page Start:
- 188
- Page End:
- 192
- Publication Date:
- 2017-12-04
- Subjects:
- Alkene -- Cyclisierungen -- Eisen -- Ketone -- Radikale
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201709659 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10665.xml