Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians. (7th May 2009)

• Record Type: Journal Article
• Authors: Neynaber, Sven; Kirschner, Christina; Kamann, Stefanie; Plewig, Gerd; Flaig, Michael J.
• Other Names: Zalaudek Iris Academic Editor.
• Is Part Of: Dermatology research and practice. Volume 2009(2009)
• Publication Date: 2009-05-07
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; 616.5005
• DOI: 10.1155/2009/607682
• Languages: English
• ISSNs: 1687-6105

Abstract

Abstract : A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.