Desmoplastic Melanoma: Report of 5 Cases. (5th November 2009)

• Record Type: Journal Article
• Authors: Manganoni, A. M.; Farisoglio, C.; Bassissi, S.; Braga, D.; Facchetti, F.; Ungari, M.; Calzavara-Pinton, P. G.
• Other Names: Argenziano Giuseppe Academic Editor.
• Is Part Of: Dermatology research and practice. Volume 2009(2009)
• Publication Date: 2009-11-05
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; 616.5005
• DOI: 10.1155/2009/679010
• Languages: English
• ISSNs: 1687-6105

Abstract

Abstract : Background. The clinical presentation of desmoplastic melanoma is often challenging. We report the experience of the Melanoma Unit of Spedali Civili University Hospital of Brescia, Italy. Method. Study subjects were drawn from 1770 patients with histologica confirmed melanoma. Within this group, desmoplastic melanoma developed in 5 patients. For each diagnosed melanoma, histological characteristics, treatment, and outcomes were evaluated. Results. Of the 5 patients described in this study, 2 were males and 3 females. The average age was 62.4 years ranging from 56 to 68 years. Breslow thickness ranged from 2.1 to 12 mm with a mean thickness of 5.8 mm. Primary treatment of 5 patients included a wide local excision of their primary lesions. Conclusions. Desmoplastic melanoma is a rare neoplasm which clinically may mimic other tumours or cutaneous infiltrate of uncertain significance. The diagnosis is hiastopathological and radical resection is necessary.