Inside Cover: Strain‐Promoted Cycloaddition of Cyclopropenes with o‐Quinones: A Rapid Click Reaction (Angew. Chem. Int. Ed. 32/2018). Issue 32 (14th June 2018)

• Record Type: Journal Article
• Authors: Gahtory, Digvijay; Sen, Rickdeb; Kuzmyn, Andriy R.; Escorihuela, Jorge; Zuilhof, Han
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 32(2018)
• Page Start: 9984
• Page End: 9984
• Publication Date: 2018-06-14
• Subjects: kinetics -- mass spectrometry -- metal-free click reactions -- monolayers -- polymer brushes; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201806126
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : Small is beautiful when it comes to click reactions. In their Communication onpage 10118 ff., H. Zuilhof et al. report the reaction between a strained alkene and an o ‐quinone, and the high yield thereof in both solution‐phase and surface‐bound reactions. Subsequently, they show that this Diels–Alder reaction outperforms faster reactions under sterically confined conditions, indicating that the cyclopropene dienophile is the highly favored reagent because of its small size.