Strain‐Promoted Cycloaddition of Cyclopropenes with o‐Quinones: A Rapid Click Reaction. (17th April 2018)

• Record Type: Journal Article
• Authors: Gahtory, Digvijay; Sen, Rickdeb; Kuzmyn, Andriy R.; Escorihuela, Jorge; Zuilhof, Han
• Is Part Of: Angewandte Chemie. Volume 130:Number 32(2018)
• Page Start: 10275
• Page End: 10279
• Publication Date: 2018-04-17
• Subjects: Kinetik -- Massenspektrometrie -- Metall-freie Click-Reaktionen -- Monolagen -- Polymerbürsten; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201800937
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: Novel click reactions are of continued interest in fields as diverse as bio‐conjugation, polymer science and surface chemistry. Qualification as a proper "click" reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain‐promoted cycloaddition between cyclopropenes and o ‐quinones in solution and on a surface. We demonstrate the "click character" of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.