Hybrid Catalysis: A Suitable Concept for the Valorization of Biosourced Saccharides to Value‐Added Chemicals. Issue 12 (2nd May 2017)

• Record Type: Journal Article
• Authors: Gimbernat, Alexandra; Guehl, Marie; Capron, Mickaël; Lopes Ferreira, Nicolas; Froidevaux, Renato; Girardon, Jean‐Sébastien; Dhulster, Pascal; Delcroix, Damien; Dumeignil, Franck
• Is Part Of: ChemCatChem. Volume 9:Issue 12(2017)
• Page Start: 2080
• Page End: 2084
• Publication Date: 2017-05-02
• Subjects: biocatalysis -- biomass -- carbohydrates -- hybrid catalysts; Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.201601633
• Languages: English
• ISSNs: 1867-3880

Abstract

Abstract: Through biomass valorization, sugars can become a major carbon resource for the production of fuels and chemicals by using catalysis. Hybrid catalysis, a direct combination of biocatalysis and chemocatalysis, may yield innovative solutions. 5‐Hydroxymethylfurfural (5‐HMF) is a platform molecule derived from glucose, for which fructose is a key intermediate. To overcome the thermodynamic enzymatic equilibrium between glucose and fructose, two methodologies based on hybrid catalysis are described herein. In the first method, the glucose isomerase and fructose‐to‐5‐HMF dehydration chemocatalysts are simultaneously implemented in a multiphasic way to imply the complexation and transport of fructose. The second method proposes a route through sorbitol, obtained by the hydrogenation of glucose. Sorbitol is then enzymatically converted into fructose, whereas regeneration of the cofactor is performed in situ with an organometallic complex as a chemocatalyst. Abstract : Mixing it up : Hybrid catalysis, which intimately combines bio‐ and chemocatalytic systems, is a promising strategy to convert bioderived molecules. We present two variations of this technology with the potential to unlocking the quantitative production of 5‐hydroxymethylfurfural from glucose.