Disparities in conditional net survival among non-Hodgkin lymphoma survivors: a population-based analysis. Issue 3 (3rd March 2016)

• Record Type: Journal Article
• Authors: Migdady, Yazan; Salhab, Mohammed; Dang, Nam H.; Markham, Merry J.; Olszewski, Adam J.
• Is Part Of: Leukemia & lymphoma. Volume 57:Issue 3(2016:Mar.)
• Page Start: 676
• Page End: 684
• Publication Date: 2016-03-03
• Subjects: Burkitt lymphoma -- conditional survival -- diffuse large B-cell lymphoma -- epidemiology -- non-Hodgkin lymphoma -- relative survival; Leukemia -- Periodicals; Lymphomas -- Periodicals; 616.99419
• DOI: 10.3109/10428194.2015.1102246
• Languages: English
• ISSNs: 1042-8194

Abstract

Abstract: We evaluated the association of baseline prognostic factors with conditional net survival among survivors of six subtypes non-Hodgkin lymphoma using the SEER program data from 2000–2012. Among 2-year survivors, further prognosis markedly improved in Burkitt's (BL) and diffuse large B-cell lymphoma (DLBCL), and became the same as for follicular lymphoma (5-year net survival ≥ 85%). Mantle cell lymphoma (MCL) demonstrated the worst prognosis of all studied histologies up to 5 years of survivorship. Age and stage lost prognostic significance in BL within 2 years from diagnosis. Racial disparities in net survival disappeared within 2 years for all subtypes, except in chronic lymphocytic leukemia, where black patients had persistently worse prognosis, and in MCL, where they had unexpectedly better prognosis than other races after 2 years. Many baseline factors may lose their initial prognostic value for lymphoma survivors, which should be considered when counseling patients about their prognosis and long-term surveillance.