The Age-Specific Association of Waist Circumference and Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus in Shandong, China. (9th September 2015)

• Record Type: Journal Article
• Authors: Xu, Lingling; Yu, Weihong; Huang, Ping; Li, Chunying; Li, Yan; Wang, Meng; Xu, Qun; Wang, Jing; Zheng, Caixia; Qu, Bin; Zhao, Yanping; Niu, Meng; Wang, Ou; Gong, Fengying
• Other Names: Perticone Francesco Academic Editor.
• Is Part Of: International journal of endocrinology. Volume 2015(2015)
• Publication Date: 2015-09-09
• Subjects: Endocrinology -- Periodicals; Endocrinology; Endocrinology -- Periodicals; Endocrine System Diseases -- Periodicals; Periodicals; 616.4
• DOI: 10.1155/2015/715871
• Languages: English
• ISSNs: 1687-8337

Abstract

Abstract : Objective . To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design . Cross-sectional evaluation of the effect of anthropometric measures on CKD risk. Setting . Outpatient Department. Subjects . T2D patients who were treated between October 2012 and May 2013. Intervention . None. Main Outcome Measure . CKD risk. Results . On average, the patients had a mean age of 60.2 years, and 40% were males. CKD was present in 46% of all the patients. In multivariate logistic regression using the imputed data, higher WC was associated with greater odds of CKD (OR = 1.019, 95% CI = 1.002–1.006, P = 0.030 ), but not BMI and WHR. Interestingly, we found that patients with very small WC seemed to have greater odds of CKD. We observed age-specific effect of WC such that the effect of WC on CKD risk is significant only in middle-aged T2D patients. Conclusion . Our study provides evidence for the association of WC with CKD in Chinese patients with T2D. T2D patients, especially middle-aged T2D patients, should reduce their WC to decrease CKD risk.