Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data. Issue 8 (14th March 2017)

• Record Type: Journal Article
• Authors: Stelzer‐Braid, Sacha; Liu, Nancy; Doumit, Michael; D'Cunha, Russell; Belessis, Yvonne; Jaffe, Adam; Rawlinson, William D.
• Is Part Of: Journal of medical virology. Volume 89:Issue 8(2017)
• Page Start: 1494
• Page End: 1497
• Publication Date: 2017-03-14
• Subjects: epidemiology -- pathogenesis -- respiratory tract -- rhinovirus; Virology -- Periodicals; 616
• DOI: 10.1002/jmv.24794
• Languages: English
• ISSNs: 0146-6615

Abstract

Abstract : Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT‐PCR in samples ( n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples ( n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5‐17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.