Lymphocytic Meningitis in Patients with Sympathetic Ophthalmia. (4th March 2017)

• Record Type: Journal Article
• Authors: Goudot, Mathilde; Groh, Matthieu; Salah, Sawsen; Monnet, Dominique; Blanche, Philippe; Brézin, Antoine P.
• Is Part Of: Ocular immunology and inflammation. Volume 25:Number 2(2017)
• Page Start: 196
• Page End: 201
• Publication Date: 2017-03-04
• Subjects: Cerebrospinal fluid pleocytosis -- lumbar puncture -- meningitis -- panuveitis -- sympathetic ophthalmia; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2017.1291841
• Languages: English
• ISSNs: 0927-3948

Abstract

Abstract : Purpose : This study aimed at reporting lymphocytic meningitis in patients diagnosed with sympathetic ophthalmia (SO). Methods : In this single-center retrospective observational case series, we reviewed cases diagnosed with SO. We analyzed the patients' inciting injuries, the characteristics of uveitis and the cerebrospinal fluid (CSF) analyses. Results : Nine patients were diagnosed with SO and CSF analyses were available in all cases. Four cases had lymphocytic pleocytosis, 3 of which showed marked CSF inflammation with more than 300 lymphocytes/mm 3 . The inciting event in these 3 patients was a globe perforation injury, whereas 4 patients without meningitis had SO following a surgical intervention. Conclusions : In this case series of patients with SO, lymphocytic meningitis was a common finding. The prevalence of meningitis in patients with SO and its value for the diagnosis of the disease needs to be further studied.