Chemical parsing: Dissecting cell dependencies with a toolkit of selective BCL-2 family inhibitors. (2nd January 2016)
- Record Type:
- Journal Article
- Title:
- Chemical parsing: Dissecting cell dependencies with a toolkit of selective BCL-2 family inhibitors. (2nd January 2016)
- Main Title:
- Chemical parsing: Dissecting cell dependencies with a toolkit of selective BCL-2 family inhibitors
- Authors:
- Leverson, Joel D.
- Abstract:
- ABSTRACT: The BCL-2/BCL-XL inhibitor navitoclax has shown promise for the treatment of cancer but on-target toxicities have limited its utility. Recently, the generation of selective BCL-2 family inhibitors has enabled a careful dissection of BCL-2 biology, and early work indicates that these molecules have improved therapeutic profiles for the treatment of cancer.
- Is Part Of:
- Molecular & cellular oncology. Volume 3:Number 1(2016)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 3:Number 1(2016)
- Issue Display:
- Volume 3, Issue 1 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 1
- Issue Sort Value:
- 2016-0003-0001-0000
- Page Start:
- Page End:
- Publication Date:
- 2016-01-02
- Subjects:
- A-1331852 -- apoptosis -- chemical parsing -- navitoclax -- venetoclax
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2015.1050155 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10596.xml