Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya. (14th July 2015)

• Record Type: Journal Article
• Authors: Kubo, Mary N.; Kayima, Joshua K.; Were, Anthony J.; McLigeyo, Seth O.; Ogola, Elijah N.
• Other Names: Ciancio Gaetano Academic Editor.
• Is Part Of: Journal of transplantation. Volume 2015(2015)
• Publication Date: 2015-07-14
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; 617.95405
• DOI: 10.1155/2015/746563
• Languages: English
• ISSNs: 2090-0007

Abstract

Abstract : Objective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods . A cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital. Sociodemographic details, blood pressure, urine albumin : creatinine ratio, and adherence using the MMAS-8 questionnaire were noted. Independent factors associated with uncontrolled hypertension were determined using logistic regression analysis. Results . 85 subjects were evaluated. Mean age was 42.4 (SD ± 12.2) years, with a male : female ratio of 1.9 : 1. Fifty-five patients (64.7%) had uncontrolled hypertension (BP ≥ 130/80 mmHg). On univariate analysis, male sex (OR 3.7, 95% CI 1.4–9.5, p = 0.006 ), higher levels of proteinuria (p = 0.042 ), and nonadherence to antihypertensives (OR 18, 95% CI 5.2–65.7, p < 0.001 ) were associated with uncontrolled hypertension. On logistic regression analysis, male sex (adjusted OR 4.6, 95% CI 1.1–19.0, p = 0.034 ) and nonadherence (adjusted OR 33.8, 95% CI 8.6–73.0, p < 0.001 ) were independently associated with uncontrolled hypertension. Conclusion . Factors associated with poor blood pressure control in this cohort were male sex and nonadherence to antihypertensives. Emphasis on adherence to antihypertensive therapy must be pursued within this population.