Unusual Pathology in a Kidney from a Heart-Transplant Patient. (5th November 2017)

• Record Type: Journal Article
• Authors: Larcher, Marie; Delas, Audey; Delmas, Clément; Cointault, Olivier; Dambrin, Camille; Del Bello, Arnaud; Kamar, Nassim
• Other Names: Keller Frieder Academic Editor.
• Is Part Of: Case reports in transplantation. Volume 2017(2017)
• Publication Date: 2017-11-05
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation; Transplantation of organs, tissues, etc; Periodicals; Periodicals; 617.954
• DOI: 10.1155/2017/1084718
• Languages: English
• ISSNs: 2090-6943

Abstract

Abstract : Acute kidney injury (AKI) is often observed after heart transplantation. In this setting, acute tubular necrosis is the main histological finding on kidneys. We report the unusual pathology found in a kidney from a heart-transplant patient. The patient experienced several hemodynamic insults, massive transfusion, and implantation of a mechanical circulatory-support device before heart transplantation: there was prolonged AKI after transplantation. A kidney biopsy revealed acute tubular necrosis and renal hemosiderosis, which was probably related to the transfusion and to mechanical circulatory-support device-induced intravascular hemolysis. Assessment of iron during resuscitation could have prevented, at least partly, AKI.