Statistical Analysis Plan for "An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery". Issue 3 (26th February 2019)

• Record Type: Journal Article
• Authors: Yuan, Ian; Olbrecht, Vanessa A.; Mensinger, Janell L.; Zhang, Bingqing; Davidson, Andrew J.; von Ungern‐Sternberg, Britta S.; Skowno, Justin; Lian, QingQuan; Song, XingRong; Zhao, Pin; Zhang, JianMin; Zhang, MaZhong; Zuo, YunXia; de Graaff, Jurgen C.; Vutskits, Laszlo; Szmuk, Peter; Kurth, Charles D.
• Editors: Anderson, Brian
• Is Part Of: Paediatric anaesthesia. Volume 29:Issue 3(2019:Mar.)
• Page Start: 243
• Page End: 249
• Publication Date: 2019-02-26
• Subjects: EEG -- isoelectric EEG -- SAP -- SAP example -- SAP template -- Statistical Analysis Plan; Pediatric anesthesia -- Periodicals; 617.96798
• DOI: 10.1111/pan.13589
• Languages: English
• ISSNs: 1155-5645

Abstract

Summary: This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.