Two new terpenoid ester glycosides from the twigs of Litsea cubeba. Issue 12 (2nd December 2018) - Wang, Ling-Yan
Abstract: A new sesquiterpenoid ester glycoside (1 ) and a new monoterpenoid ester glycoside (2 ) have been isolated from an ethanol extract of the twigs of Litsea cubeba . Their structures were elucidated by extensive 1D- and 2D-NMR experiments, and the absolute configurations were determined by chemical methods, specific rotation, and a combination of experimental and theoretically calculated electronic circular dichroism spectra. Compound1 exhibited selective cytotoxicity against A549 and HCT-8 cell lines with the IC50 values of 8.9 and 9.6 μ M, respectively.