Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys. (23rd December 2010)

• Record Type: Journal Article
• Authors: Shkoda, I.; Lapin, E.; Rosenbluth, E.; Perk, S.; Geva, Z.; Inbar, A.; Davidson, I.
• Other Names: Matrosovich Mikhail Academic Editor.
• Is Part Of: Influenza research and treatment. Volume 2011(2011)
• Publication Date: 2010-12-23
• Subjects: Influenza -- Periodicals; Influenza, Human; Virus Diseases; Viruses; Influenza; Electronic journals; Periodical; Electronic journals; Periodicals; 616.203
• DOI: 10.1155/2011/285218
• Languages: English
• ISSNs: 2090-1380

Abstract

Abstract : An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.