A Photocatalytic Meerwein Approach to the Synthesis of Isochromanones and Isochromenones. Issue 15 (27th January 2017)

• Record Type: Journal Article
• Authors: Crespi, Stefano; Jäger, Stefanie; König, Burkhard; Fagnoni, Maurizio
• Other Names: König Burkhard guestEditor.
• Is Part Of: European journal of organic chemistry. Issue 15(2017)
• Page Start: 2147
• Page End: 2153
• Publication Date: 2017-01-27
• Subjects: Photocatalysis -- Radicals -- Diazonium salts -- Cyclization -- Reaction mechanisms; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201601458
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : A visible‐light Ru II photoredox Meerwein synthesis of isochromanones and isochromenones is described starting from diazonium salts of differently substituted anthranilic acids and various alkenes. This approach has allowed the reliable and efficient preparation of structures found in many biologically active molecules or used in materials chemistry. Abstract : A mild and facile photoredox approach towards synthetically interesting isochromanones and isochromenones is presented. The diazonium salts of various functionalised anthranilic acids have been converted by reaction with various alkenes into the desired bi‐ and tricyclic compounds in good to excellent yields.